[Company Logo Image] Compound validation and profiling in vitro and in vivo
Improved clinical predictability of preclinical studies
Subcutaneous and orthotopic human xenografts
Genetically modified organ specific tumour models
Receptor tyrosine kinase-driven breast cancer model

         Preclinical Concept Validation

Angiogenesis in vivo Model


Syngeneic tumour models
Pharmacokinetic studies
  Toxicology (GLP)
  Histology (Frozen Sections and Paraffin Embedded Sections)


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Human tumour xenografts are screening tools for for anticancer drug development. vivoPharm uses cell lines of different human tumour types. All cell lines were obtained from ATCC and grow at controlled low passage number. Tumours grow subcutaneously in nude mice following cell injection.
The tumour models at vivoPharm include carcinomas of the following organs in nude mice:

Cell Line
Breast MDA MB-435, MDA MB-468, MDA MB231, T47D
Colon HCT-15, Colo 205, HT29, HCT-116
Kidney A498
Lung NIH H460, NCI H596, A549
Ovary OVCAR-3
Prostate PC-3, PC-3M, Du145, LNCaP
Melanoma A375
Customers cell line or a cell line of your request

For price quotes please contact sales@vivoPharm.com


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Last modified: 18-Dec-2003